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Eradicate
Black
Sorcery
2BB
Remove target nonblack creature from the game.
Search its controller's graveyard, hand, and library for all copies of that card and remove them from the game.
That player then shuffles his or her library.
(From Urza's Destiny)
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Pretty good card, hey? With this card, you can wipe out any annoying creature permanently. But is that all it can do?
Here's a little combo that you can build a 1.5 deck around. It's a simple combo but it has some devastating results.
Here it is:
 
First of all, you have to find a way to turn your opponent's lands into creatures.
The best way to do this is to add green to the deck:
 
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Quiron Druid
Green
Creature-Druid
2G
G, Tap: Target Land becomes a 2/2 green creature permanently. That land still counts as a land.
(From Visions)
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Verdant Touch
Green
Sorcery
1G
Buyback 3
Target land becomes a 2/2 creature permanently
(From Stronghold)
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Jolrael, Empress of Beasts
Green
Creature-Spellshaper Legend
3GG
2G, Tap, Discard two cards from your hand: Until end of turn, all lands target player controls are 3/3 creatures that are still lands.
(From Prophecy)
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From here on, all you have to do is turn one of your opponent's basic lands into a creature, and Eradicate it. 
For instance, if you turned your opponent's "Mountain" into a 2/2 creature via Verdant Touch, Eradicate would kill it.
Then, you get to search his graveyard, library, and hand for all copies of "Mountain" and remove it from the game.
From that point on, your opponent's only Mountains are the ones he has in play. Repeat this, wiping out all of his land.
 
Then, now that you're playing Green-Black, you can activate Jolrael's ability, turning his lands into creatures, and then activate
a Pernicious Deed. Since his lands are creatures with casting cost of zero, they get destroyed (along with his best permanents),
leaving him with no lands in play, and no lands to draw.
 
Another way to destroy his lands in play is with a Desolation Angel, which would require you to splash in white. Not a problem
with Birds of Paradise and the new Invasion-Block lands.
 
This combo is strictly a "fun" combo. It is pretty difficult to pull off, but is hilarious nonetheless. Watching your opponent sit there
with no permanents, and drawing no lands is pure entertainment.