with the popular mr. mime around, the game is not the same. first, lets look at the card...
 
Basic
Mr. Mime            40HP
Poke' Power; invisible wall
   Whenever an attack (including your own)does thirty or more damage to mr. mime(after applying weakness and resistance) prevent that damage. (any other effects of attack still happen) this power can't be used if Mr. mime is asleep, confused, or parylized.
 
(psy, col)Meditate  does 10 damage + 10 damage for each damage counter on the defending pokemon                                                                                      10+
 
weakness; psy          resistance; none          retreat; 1
 
so, along with popularity, comes death. there are, all in all, the 4AWESOME mr. mime killers:
 
Nidoking
Muk
Dragonair
Ratatta
 
BUT along with popularity comes the ULTIMATE combo.....
 
 
MR. MIME  +  DEFENDER!!!!!!!!!!!(can we say "unstoppable"?)
 
therefore, even though there are some deadly "mime killers" mr mime also has an awesome combo within itself.  Try it, you may like the combo more than ever before..... 
 
~RoSsMaN~